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KMID : 1189420060190010001
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2006 Volume.19 No. 1 p.1 ~ p.10
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The Experimental Studies on Anti-bacterial Effect of Tangpo-san on Three species of causative bacteria of Keratitis
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Kang Sung-Koo
Yoo Jin-Gon
Choi Kwan-Ho
Seo Hyeong-Sik
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Abstract
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This experimental study was performed to investigate the effect of herbal eye drops, Tangpo-san and Coptidis rhizoma on Staphylococcus aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa keratitis. The following results were obtained by using Minimum inhibition Concentration(MIC) and inhibition Zone. 1. MIC on Staphylococcus aureus in Tangpo-san was 100%, in Coptidis rhizoma was 100% and in Cravit was 0.1% 2. MIC on Staphylococcus epidermidis in Tangpo-san was 100%, in Coptidis rhizoma was 10% and in Cravit was 0.1%. 3. MIC on Pseudomonas aeruginosa in Tangpo-san, Coptidis rhizoma was not showing and in Cravit was 0.1%. 4. The size of inhibition zone on Staphylococcus aureus for Tangpo-san was 13.3mm in 50ul, for Coptidis rhizoma was 26mm in 50ul and for Cravit was 31mm in 50ul, showing the highest antibacterial effect. 5. The size of inhibition zone on Staphylococcus epidermidis for Tangpo-san was 16mm in 50ul, for Coptidis rhizoma was 25mm in 40ul and for Cravit was 34mm in 50ul, showing the highest antibacterial effect. 6. The size of inhibition zone on Pseudomonas aeruginosa for Tangpo-san, Coptidis rhizoma was not and for Cravit was 24.7mm in 50ul, showing the antibacterial effect. In addition, the results shows that the herbal eye drops, Tangpo-san and Coptidis rhizoma can be used to cure Staphylococcus aureus, Staphylococcus epidermidis keratitis and if further study is performed, the use of herbal eye drops will be valuable and beneficial in the clinical medicines.
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KEYWORD
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Staphylococcusaureuskeratitis, Staphylococcusepidermidiskeratitis, Pseudomonasaeruginosakeratitis, Herbaleyedrops(Tangpo-san, CopitdisRhizoma), MIC, Inhibitionzone, Growthinhibitioneffect
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